Cellular inhibitor of apoptosis protein (cIAP) is a convergent hub that couples BCR-CD40 signal dynamics to B cell fate

BCR and CD40 signals are integrated to shape B cell transcriptional output, but how the two pathways are coordinated at the level of individual signaling nodes is incompletely understood.

BCR and CD40 signals are integrated to shape B cell transcriptional output, but how the two pathways are coordinated at the level of individual signaling nodes is incompletely understood. Using primary mouse B cells stimulated with anti-IgM, anti-CD40, or both (Both), we defined…