Exponential growth and neuronal yield in the vertebrate developing retina are mediated by Hedgehog signaling

The balance between self-renewal and terminal differentiation of neural progenitors is regulated by a complex interplay of signaling pathways that set the spatial and temporal cues that ultimately shape and organize neurogenic tissues.

The balance between self-renewal and terminal differentiation of neural progenitors is regulated by a complex interplay of signaling pathways that set the spatial and temporal cues that ultimately shape and organize neurogenic tissues. In this contribution, we combine in toto…