Science & ResearchJul 22, 2026
Genetic background sets the trajectory of experimental cancer evolution.
Human cancers are heterogeneous 1 . Dissecting how germline genetic variation and environmental factors shape tumour evolution using human datasets is limited by inherent diversity in genetic backgrounds 2 and environmental exposures 3-5…
Human cancers are heterogeneous 1 . Dissecting how germline genetic variation and environmental factors shape tumour evolution using human datasets is limited by inherent diversity in genetic backgrounds 2 and environmental exposures 3-5 . Here, to overcome these limitations, we…
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