Gut microbiota generate dinitrosyl iron complexes with cardiometabolic benefits.

Gut bacteria affect host physiology, but the underlying mechanisms are not completely understood.

Gut bacteria affect host physiology, but the underlying mechanisms are not completely understood. We identify a pathway whereby gut microbes convert inorganic nitrate and non-heme iron into mobile bioactive dinitrosyl iron complexes (DNICs) that are distributed systemically and…