Science & ResearchJul 16, 2026
Phosphorylation of the AP2 μ2 subunit by p70S6 kinase facilitates clathrin-mediated endocytosis.
Clathrin-mediated endocytosis (CME) internalizes cell-surface receptors via clathrin-coated invaginations of the plasma membrane.
Clathrin-mediated endocytosis (CME) internalizes cell-surface receptors via clathrin-coated invaginations of the plasma membrane. Both clathrin and endocytic cargo are recruited to these sites by the adaptor protein complex AP2. AP2 cycles between a closed cytoplasmic…
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