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Science & ResearchAug 21, 2026

Genetic screening identifies glial adenosine as a therapeutic target in alpha-synucleinopathy

Neuronal alpha-synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB), lack disease-modifying therapies.

Neuronal alpha-synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy bodies (DLB), lack disease-modifying therapies. We developed a Drosophila model for identifying novel glial-based therapeutic targets for alpha-synucleinopathies. In this model, human…

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