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Science & ResearchSep 2, 2026

Structure and operating principles of a monkeypox virus replisome.

Poxviruses are double-stranded DNA viruses with large genomes.

Poxviruses are double-stranded DNA viruses with large genomes. Among them, monkeypox virus (MPXV) has been responsible for two recent public health emergencies as declared by the World Health Organization 1 . The MPXV polymerase comprises three subunits-a catalytic subunit (F8)…

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