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Science & ResearchJul 30, 2026

Anticodon nucleotide modifications affect translational tuning by the ribosomal CAR surface

Nucleotide modifications of the tRNA anticodon can affect protein translation fidelity and speed.

Nucleotide modifications of the tRNA anticodon can affect protein translation fidelity and speed. Chemical modifications of the anticodon nucleotide 34 are regulated under cellular stress and associated with several translational defects and pathologies. Here, we investigate how…

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