BRCA2 and RAD54B FxPP motifs Bind DMC1 Filaments through Persistent and Transient Interfaces

During meiosis, double-strand DNA breaks are programmed to initiate homologous recombination.

During meiosis, double-strand DNA breaks are programmed to initiate homologous recombination. The DMC1 recombinogenic filament is central to the repair of these breaks. However, the three-dimensional structures of the protein-protein interfaces regulating the assembly and…