HaloUMI: Physics-informed analysis of inhibition halo assays

Quantification of microbial growth inhibition is central to assays ranging from antibiotic susceptibility of bacteria to sensitivity of yeasts to antifungal therapeutics.

Quantification of microbial growth inhibition is central to assays ranging from antibiotic susceptibility of bacteria to sensitivity of yeasts to antifungal therapeutics. Classical analysis approaches derive from zone-of-inhibition (termed halo) formats using filter paper discs,…