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Science & ResearchAug 18, 2026

Cross-Species BAC Transgenesis Reveals Long-Range Regulation Drives Variation in Brain Oxytocin Receptor Expression and Social Behaviors

Although oxytocin (OXT) exhibits a highly conserved neuroanatomical pattern among vertebrates, the distribution of OXT receptor (OXTR) in brain varies considerably across species and is associated with species-typical social behavior.

Although oxytocin (OXT) exhibits a highly conserved neuroanatomical pattern among vertebrates, the distribution of OXT receptor (OXTR) in brain varies considerably across species and is associated with species-typical social behavior. To investigate the genomic basis of the…

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