The molecular architecture of mammalian vitreous body collagen fibrils.

Collagen, a fundamental constituent of the extracellular matrix, has long remained elusive to high-resolution structural characterization.

Collagen, a fundamental constituent of the extracellular matrix, has long remained elusive to high-resolution structural characterization. Using a tailored system and optimized cryo-electron microscopy processing for long-period filaments, we determined the structure of native…