Science & ResearchJul 31, 2026
Bacteria Hijack a Host Metabolite via Three Distinct Sensors to Orchestrate Infection
The crisis of antimicrobial resistance demands new strategies that circumvent conventional killing.
The crisis of antimicrobial resistance demands new strategies that circumvent conventional killing. Here, we show that Yersinia pseudotuberculosis intercepts host mesifurane, a mimic of quorum-sensing signal AI-2. Rather than acting through a single receptor, mesifurane is…
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