Science & ResearchJul 28, 2026
H4K20me3 and CTCF act reciprocally at TAD boundaries to regulate cell state transitions
Reversible transitions between proliferative and quiescent cell states involve widespread gene expression changes despite stable topologically associating domain (TAD) positioning.
Reversible transitions between proliferative and quiescent cell states involve widespread gene expression changes despite stable topologically associating domain (TAD) positioning. We report a reciprocal antagonism between TAD boundary element CTCF and histone modification…
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