Science & ResearchAug 17, 2026
Translesion synthesis protein ImuA from Mycolicibacterium smegmatis is a hexameric helicase-nuclease
Translesion DNA synthesis (TLS) enables DNA replication across damaged DNA and promotes stress-induced mutagenesis that contributes to antibiotic resistance in bacteria.
Translesion DNA synthesis (TLS) enables DNA replication across damaged DNA and promotes stress-induced mutagenesis that contributes to antibiotic resistance in bacteria. The conserved ImuABC mutasome is essential for TLS in many bacterial species, yet the molecular function of…
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