Science & ResearchAug 9, 2026
Engineered protein circuits for cancer therapy
A central challenge in cancer therapy is selectively killing cancer cells while minimizing resistance.
A central challenge in cancer therapy is selectively killing cancer cells while minimizing resistance. Here, we engineer modular protease-based protein circuits that sense mutant RAS, the most frequently mutated oncogene in cancer, and conditionally activate cell death.…
Sign in to learn & save →
The frontier is open to all. Sign in to learn this from first principles and save it to your knowledge base.