Science & ResearchAug 14, 2026
SARS-CoV-2 protein ORF3a induces Atg8ylation of lysosomal membranes
Atg8ylation is an autophagy associated response to membrane damage that recruits mammalian ATG8 proteins (mATG8s) to damaged membranes to promote their repair or removal.
Atg8ylation is an autophagy associated response to membrane damage that recruits mammalian ATG8 proteins (mATG8s) to damaged membranes to promote their repair or removal. Here, we show that the SARS-CoV-2 protein ORF3a induces lysosomal membrane atg8ylation and that this…
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