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Science & ResearchJul 30, 2026

Phase 2b Trial of a Na V 1.8 Inhibitor for Acute Pain.

Na v 1.8, a voltage-gated sodium channel expressed in the peripheral nervous system, has a critical role in pain signaling.

Na v 1.8, a voltage-gated sodium channel expressed in the peripheral nervous system, has a critical role in pain signaling. Previous trials of Na V 1.8 inhibitors have shown effectiveness in reducing postoperative pain. We conducted a phase 2b, double-blind, randomized,…

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