← The frontier
Science & ResearchAug 24, 2026

DDIAS shields single-stranded DNA in mitosis and promotes vertebrate brain development.

DNA double-strand breaks and unresolved DNA replication intermediates are particularly dangerous during mitosis.

DNA double-strand breaks and unresolved DNA replication intermediates are particularly dangerous during mitosis. Paradoxically, cells inactivate canonical DNA repair mechanisms during chromosome segregation in favor of alternative pathways that depend on TOPBP1 and CIP2A, but…

The frontier is open to all. Sign in to learn this from first principles and save it to your knowledge base.