Science & ResearchAug 4, 2026
A benchmarking framework for single-cell genome-scale metabolic model construction
Single-cell genome-scale metabolic models (scGEMs) enable characterization of metabolic heterogeneity underlying cellular states and phenotypes.
Single-cell genome-scale metabolic models (scGEMs) enable characterization of metabolic heterogeneity underlying cellular states and phenotypes. However, methodological choices during scGEM construction can substantially alter model structure and predictions, challenging the…
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