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Science & ResearchAug 22, 2026

Real-time repository-scale spectral search and global molecular networking with HNSW-MS

Spectral similarity comparison is the basis of mass spectrometry-based metabolomics, underpinning library matching, molecular network construction, and repository searches such as MASST.

Spectral similarity comparison is the basis of mass spectrometry-based metabolomics, underpinning library matching, molecular network construction, and repository searches such as MASST. Public repositories now exceed billion spectra, and exhaustive pairwise comparison is…

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