Science & ResearchAug 17, 2026
Endothelial ANGPT2 insufficiency impairs retinal vascularization with ROP-like neovascular tufts
ANGPT2 is widely recognized as a critical regulator of pathological neovascularization.
ANGPT2 is widely recognized as a critical regulator of pathological neovascularization. By analyzing scRNA-seq data from neonatal retinas, we demonstrate that Angpt2 transcripts are highly enriched in tip cells relative to other endothelial subtypes, where Angpt1/4 expression is…
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