Pharmacological blockade of opioid receptors in the ventrolateral periaqueductal gray does not affect avoidance acquisition or performance in rats

Avoidance learning involves associating a behavioral response with the omission of an expected threat, but the neural mechanisms that drive this learning remain unclear.

Avoidance learning involves associating a behavioral response with the omission of an expected threat, but the neural mechanisms that drive this learning remain unclear. Research on fear extinction points to a critical role for opioid receptors in the ventrolateral…