Science & ResearchAug 12, 2026
Asymmetric DNA targeting by RNA-guided TIGR-Tas systems
Tandem interspaced guide RNA (TIGR)-TIGR-associated (Tas) are RNA-guided defense systems, which use a dual-repeat or stem-loop tigRNA to direct a Tas dimer to DNA targets through RNA-DNA heteroduplex formation between both DNA strands.
Tandem interspaced guide RNA (TIGR)-TIGR-associated (Tas) are RNA-guided defense systems, which use a dual-repeat or stem-loop tigRNA to direct a Tas dimer to DNA targets through RNA-DNA heteroduplex formation between both DNA strands. While previous work has shown the basic…
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