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Science & ResearchJul 22, 2026

Structural basis of the RNA-editing cascade in trypanosome mitochondria.

The molecular mechanism of uridine insertion-and-deletion mRNA editing in trypanosome mitochondria 1-4 has remained unclear because of the highly dynamic nature of the underlying multi-enzyme machinery 5 .

The molecular mechanism of uridine insertion-and-deletion mRNA editing in trypanosome mitochondria 1-4 has remained unclear because of the highly dynamic nature of the underlying multi-enzyme machinery 5 . Here, we define editosomes as supramolecular assemblies formed by the…

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