Science & ResearchJul 21, 2026
A Pan-Cancer Multi-Omic Analysis of Copy Number Signature Clusters and Genomic Instability
Copy number alterations (CNAs) are major contributors to genomic instability in cancer, and copy number signatures (CNS) provide a compact representation of the processes shaping CNA landscapes.
Copy number alterations (CNAs) are major contributors to genomic instability in cancer, and copy number signatures (CNS) provide a compact representation of the processes shaping CNA landscapes. However, the relationships among existing CNS frameworks and their predictability…
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