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Science & ResearchAug 22, 2026

Imaging-Based Age- and Sex-Related Cardiovascular and Skeletal Phenotypes in Fbn1C1041G/+ Mice

Marfan syndrome is a multisystem connective tissue disorder with age-dependent and sex-dependent phenotypic variability.

Marfan syndrome is a multisystem connective tissue disorder with age-dependent and sex-dependent phenotypic variability. This study characterized early cardiovascular, valvular, transmitral flow, and skeletal changes in Fbn1C1041G/+ mice. Male and female wild-type and…

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