Tertiary lymphoid structures harbour stem-like tumour-specific T cells.

Tertiary lymphoid structures (TLSs) are associated with improved responses to immune checkpoint blockade across solid tumours 1,2 , but how they impact the phenotypic properties of tumour-specific T cells remains unclear.

Tertiary lymphoid structures (TLSs) are associated with improved responses to immune checkpoint blockade across solid tumours 1,2 , but how they impact the phenotypic properties of tumour-specific T cells remains unclear. Here we found, across 24 treatment-naive renal cell…