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Science & ResearchSep 5, 2026

PoolParty: streamlined design of DNA sequence libraries in Python

Background: Computationally designed DNA sequence libraries are essential components of massively parallel reporter assays (MPRAs), deep mutational scanning (DMS) experiments, and other multiplex assays of variant effect (MAVEs).

Background: Computationally designed DNA sequence libraries are essential components of massively parallel reporter assays (MPRAs), deep mutational scanning (DMS) experiments, and other multiplex assays of variant effect (MAVEs). They are also increasingly used in silico to…

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