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Science & ResearchSep 3, 2026

Histone H3K9 methylation and Heterochromatin Protein 1 do not limit DNA accessibility in living S. pombe cells

Chromatin is intrinsically repressive, limiting access to DNA, implying a major regulatory role.

Chromatin is intrinsically repressive, limiting access to DNA, implying a major regulatory role. Studies with nuclei support this model. However, we have shown previously that genomic DNA is completely accessible in living budding yeast and human cells, except for centromeric…

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