Spatial transcriptomics resolves ductal TREM2+ and stromal FOLR2+ macrophages in the normal human breast at microanatomical resolution

Macrophage identities are coupled to specialized roles through their local niches of residence.

Macrophage identities are coupled to specialized roles through their local niches of residence. In the breast, macrophages contribute to epithelial development and re-modeling, immune surveillance, and angiogenesis. These diverse functions imply a spatial organization of…