Science & ResearchJul 21, 2026
Systematic multivariate analysis of chromatin complex dependencies reveals Set1C/COMPASS as a melanoma-enriched epigenetic vulnerability
Epigenetic dysregulation is a common feature of cancer.
Epigenetic dysregulation is a common feature of cancer. It creates vulnerabilities arising from an increased reliance on chromatin-based mechanisms that sustain malignant transcriptional states. While many chromatin regulators are broadly required for cellular viability, others…
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