Polarized F-actin establishes cell interactions required for the formation of a stem cell niche

Lifelong stem cells are maintained by a cellular microenvironment called the niche, which enables tissue homeostasis.

Lifelong stem cells are maintained by a cellular microenvironment called the niche, which enables tissue homeostasis. Proper niche construction is essential for persistent function, but studying niche formation is challenged by the inaccessibility of most niches to in vivo…