Ophthalmate tripeptide is a signaling molecule that regulates striatal neurotransmission

Dopamine has long been regarded as the key neurotransmitter governing motor function through the direct and indirect striatal outflow pathways.

Dopamine has long been regarded as the key neurotransmitter governing motor function through the direct and indirect striatal outflow pathways. However, the tripeptide ophthalmate (ophthalmic acid, OA), a glutathione analog, has recently emerged as another regulator of motor…