Deep axonal proteomics of human iPSC-derived neurons by microfluidic separation and DIA-MS

One of the defining features of neurons is their compartmentalisation into soma, dendrites and axon.

One of the defining features of neurons is their compartmentalisation into soma, dendrites and axon. Axons are highly specialised for the transmission of signals over long distances but also exhibit unique vulnerabilities in the context of neurodegeneration, implying a…