Natural history and clinical impact of epilepsy in adults with Down syndrome: a multicentre clinical study.

As individuals with Down syndrome age, they face high risks of Alzheimer's disease and epilepsy.

As individuals with Down syndrome age, they face high risks of Alzheimer's disease and epilepsy. With symptomatic Alzheimer's disease, late-onset myoclonic epilepsy in Down syndrome (LOMEDS) often emerges. We aimed to examine how epilepsy develops in Down syndrome, its timing…