Dual lineages of Langerhans cells cooperate to restore the immune barrier after skin injury

Langerhans cells (LCs) are key immune sentinels of the epidermis.

Langerhans cells (LCs) are key immune sentinels of the epidermis. How this network reorganizes to safeguard epidermal immunity after injury has remained unclear. Here, we uncover a previously unrecognized two-lineage program of LC repopulation during wound repair. Classically,…