Science & ResearchAug 1, 2026
Common schizophrenia heritability concentrates in an evolutionarily young, brain-regulatory subset of fine-mapped credible-set variants
Common variation explains a substantial fraction of schizophrenia heritability, yet why these risk alleles persist remains unresolved.
Common variation explains a substantial fraction of schizophrenia heritability, yet why these risk alleles persist remains unresolved. Of 20,766 fine-mapped PGC3 schizophrenia credible-set variants, the 4,918 with an allele-age estimate, brain-versus-blood regulatory specificity…
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