Science & ResearchJul 17, 2026
Sustained epigenetic rejuvenation of serially engrafting human iPSC-derived HSCs
Hematopoietic stem cell (HSC) function declines with age, contributing to immunosenescence and inferior transplantation outcomes.
Hematopoietic stem cell (HSC) function declines with age, contributing to immunosenescence and inferior transplantation outcomes. Here, we generated iPSC-derived HSCs (iHSCs) from multiple adult donors and performed integrated epigenetic, transcriptional, telomeric, and…
Sign in to learn & save →
The frontier is open to all. Sign in to learn this from first principles and save it to your knowledge base.