Science & ResearchJul 24, 2026
Rat mediodorsal thalamic subdivisions differentially modulate the sensory and affective components of pain through distinct prefrontal pathways.
The mediodorsal thalamus (MD) modulates pain through thalamocortical regulation of the mPFC.
The mediodorsal thalamus (MD) modulates pain through thalamocortical regulation of the mPFC. Yet, MD is often treated as a single anatomical and functional entity despite marked internal heterogeneity. Here, we tested whether medial-central MD (MDmc) and lateral MD (MDl)…
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