Distinct transcriptomic and hierarchical organization associated with brain hyperconnectivity and hypoconnectivity in autism spectrum disorder

Functional hyperconnectivity and hypoconnectivity in autism spectrum disorder (ASD) are typically treated as opposing expressions of a single circuit-level disturbance, but their molecular and hierarchical basis remains unclear.

Functional hyperconnectivity and hypoconnectivity in autism spectrum disorder (ASD) are typically treated as opposing expressions of a single circuit-level disturbance, but their molecular and hierarchical basis remains unclear. We combined resting-state fMRI from 1,737…