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Science & ResearchAug 1, 2026

Pangenome Graph Node-Phenotype Association shows GWAS-like quality results with only few individuals

Purpose: We introduce GraNPA, standing for Graph Node-Phenotype Associa- tion, a method performing a GWAS-like analysis on a pangenome variation graph (PVG) built using a small number of individual genome sequences, without the need for…

Purpose: We introduce GraNPA, standing for Graph Node-Phenotype Associa- tion, a method performing a GWAS-like analysis on a pangenome variation graph (PVG) built using a small number of individual genome sequences, without the need for additional population materials or kinship…

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