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Science & ResearchAug 1, 2026

Global analysis of the cold-shock response in the model antibiotic producing actinomycete, Streptomyces coelicolor A3(2)

Cold-shock adaptation is essential for the survival of soil-dwelling sessile streptomycetes exposed to fluctuating environmental temperatures, yet the precise regulatory mechanisms underlying this response remain poorly understood.

Cold-shock adaptation is essential for the survival of soil-dwelling sessile streptomycetes exposed to fluctuating environmental temperatures, yet the precise regulatory mechanisms underlying this response remain poorly understood. Here, we investigated the global…

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