Science & ResearchJul 31, 2026
Hypothalamic oligodendrocytes regulate systemic energy balance through Notch-dependent state transitions
The central mechanisms through which glial cells regulate whole-body metabolism remain poorly understood.
The central mechanisms through which glial cells regulate whole-body metabolism remain poorly understood. Here, we identify Notch signaling in hypothalamic oligodendrocyte lineage cells as a previously unrecognized regulator of systemic energy homeostasis. Pharmacological…
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