Science & ResearchAug 3, 2026
crispAIPE: Probabilistic Modelling of Prime Editing Variant Correction Efficiency
Prime editing installs precise substitutions, insertions, and deletions without double-strand breaks or donor templates, but the efficiency of an individual pegRNA design is hard to predict in advance, and existing tools give only point…
Prime editing installs precise substitutions, insertions, and deletions without double-strand breaks or donor templates, but the efficiency of an individual pegRNA design is hard to predict in advance, and existing tools give only point estimates, leaving designers unable to…
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