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Science & ResearchSep 1, 2026

Ratiometric transcriptional activation by protein degradation.

Cells can respond to alterations in the abundances of specific proteins through transcriptional outputs.

Cells can respond to alterations in the abundances of specific proteins through transcriptional outputs. Synthetic approaches inspired by native post-transcriptional circuits that convert protein abundance changes into programmable gene expression would be transformative. Here,…

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