← The frontier
Science & ResearchJul 24, 2026

Opposite and complementary roles of the two calcium thresholds for inducing LTP and LTD in models of striatal projection neurons

Synaptic plasticity has been shown to occur when calcium, flowing into the synapse due to incoming stimuli, surpasses a threshold level.

Synaptic plasticity has been shown to occur when calcium, flowing into the synapse due to incoming stimuli, surpasses a threshold level. This threshold level is modifiable through a process called metaplasticity. Some neurons, such as the striatal projection neurons, use…

The frontier is open to all. Sign in to learn this from first principles and save it to your knowledge base.