Science & ResearchAug 19, 2026
Synthesis of pyrroles from isoxazoles by an O-to-C skeletal edit
Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6 A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a com…
Nature, Published online: 19 August 2026; doi:10.1038/s41586-026-10933-6 A one-pot skeletal-editing reaction replaces isoxazole oxygen with carbon to form challenging pyrroles, enabled by an N-propargylic enaminone intermediate and a computational model predicting reaction…
Sign in to learn & save →
The frontier is open to all. Sign in to learn this from first principles and save it to your knowledge base.