Science & ResearchAug 2, 2026
Reconstructing whole-organism cell phylogenies with resolved ancestral transcriptional states
Combining cell lineage tracing with single-cell RNA sequencing can reconstruct a phylogenetic tree to integrate single-cell transcriptomic atlas.
Combining cell lineage tracing with single-cell RNA sequencing can reconstruct a phylogenetic tree to integrate single-cell transcriptomic atlas. However, the internal nodes of this tree - representing ancestral cells - remain transcriptionally silent, preventing along-lineage…
Sign in to learn & save →
The frontier is open to all. Sign in to learn this from first principles and save it to your knowledge base.