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Science & ResearchAug 28, 2026

Aficamten for Symptomatic Nonobstructive Hypertrophic Cardiomyopathy.

Nonobstructive hypertrophic cardiomyopathy (HCM) is a common condition that is associated with substantial morbidity and no proven medical therapy.

Nonobstructive hypertrophic cardiomyopathy (HCM) is a common condition that is associated with substantial morbidity and no proven medical therapy. Whether treatment with aficamten, a cardiac myosin inhibitor, can benefit patients with this condition is unknown. In this phase 3,…

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